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REDEFINE 1 Trial Finds CagrilintideSemaglutide Combo Delivers Over 20% Weight Loss in Majority of Patients

Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)

Chiou HY, Chiou ST, Hsu YH, Chou YL, Tseng CH, Wei ML, Chen C

De Beck KO, Vermeersch P, Verschueren P, Westhovens R, Marin G, Blockmans D, et al

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