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In mice, the inguinal depot is highly susceptible to undergo browning 29,39 , and our data align with previous reports demonstrating that induction of a brown-like phenotype selectively in iWAT improves metabolic health 40,41

The administration of celecoxib, a selective COX-2 inhibitor, improved depressive behavior in experimental rats by altering age-dependent increases in the levels of proinflammatory cytokines and anti-inflammatory corticosterone in the hippocampus [138]

doi: 10.1021/acsnano.4c16058 83 BitayEGergelyALSzabZI

Unraveling cadmium toxicity and tolerance in plants: insights into regulatory mechanisms

Psychiatry 2 , 6 (2003)