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M., and Touyz, R
pmid:22534974
Jaquet V, Marcoux J, Forest E, et al

CLIC proteins contain Grx-like active site motiv, Cys-Pro-(Phe/Ser)-(Ser/Cys), present also in O-class GSTs [208,220,221]

While IGF-1 LR3 was engineered for extended half-life and systemic activity, IGF-1 DES follows the opposite strategy: very short half-life (20-30 minutes) but extreme potency at the site of injection