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Thus, epigenetic mechanisms may be involved in the attenuated metastasis that has been observed in animal models and patients following administration of vitamin C (Padayatty et al., 2006
Plant Physiol 134:10271038
Conversely, reports suggest that ChaC1 overexpression may be associated with tumor cell dedifferentiation, proliferation, invasion and migration, leading to lower patient survival rates (73,74)
Notably, catechin inhibits lactate dehydrogenase A (LDHA), blocking pyruvate conversion to lactate
13(1): doi: 10.1177/1557988318818280 9
