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5 Chylomicron liver reuptake During passage through the hepatic sinusoids, remnant particles are further hydrolyzed by hepatic triglyceride lipase (HL) and gain additional apoE, which makes it possible for them to bind to and be taken up by proteins on the surface of liver cells, such as the LDL receptor (LDLR), LDL-like receptor protein-1 (LRP-1), and the heparin sulfate proteoglycan syndecan-1 ( Figure 4 )

Possible explanations include atypical dietary intake, altered gut microbial liberation of coumarin from plant polyphenols, or reduced hepatic detoxification

Factors influencing gel-strengthening at the mucoadhesive-mucus interface

To address this gap, this study employed an integrated approach, combining meta-analysis, network pharmacology, Mendelian randomization, GEO data analyses, molecular docking, and molecular dynamics simulation to comprehensively evaluate the efficacy, safety, and underlying pharmacological mechanisms of sulforaphane in ASD

Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis