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Keywords: pharmacokinetics, tissue distribution, biotransformation, panduratin A, Boesenbergia rotunda , COVID-19 Graphical Abstract: Introduction In 2020, the world was faced with the event with the greatest impact in modern history, the outbreak of Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2)

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It is metabolized through anabolic and catabolic pathways (Sethy and Kundu, 2021)

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