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127,128,129 To date, studies have uncovered that the lactate shuttle is involved in the TME during interactions between various cell populations and this aspect of lactate shuttling is defined as metabolic symbiosis, which is a vital phenomenon of tumor biology
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FIGURE 5 7.6.1
A NRF2s downstream antioxidant enzyme, NAD(P)H-quinone oxidoreductase 1 (NQO1), catalyzes the conversion of quinone to hydroquinone while lowering the formation of semi-hydroquinone and ROS
Neurology 61(11 Suppl 6):S51S54
