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Introduction Diabetes mellitus (DM) is a chronic metabolic disorder resulting from the interplay of genetic and environmental factors, with its prevalence rising annually ( Presently, the primary strategies in Western medical treatment include glycemic control, infection management, removal of necrotic tissue, decompression, hyperbaric oxygen therapy, and restoration of blood flow ( Pathophysiology of diabetic foot ulcers The pathogenesis of diabetic foot ulcers is predominantly linked to neuropathy, vasculopathy, and infection and inflammation ( Figure 1 )

A systematic exploration of unexploited genes for oxidative stress in Parkinsons disease

Release 145 , 182195 (2010)

Emerging roles of metallothioneins in beta cell pathophysiology: beyond and above metal homeostasis and antioxidant response

Mol Psychiatry (2012) 17:389401.10.1038/mp.2011.165 10 SchaeferGBMendelsohnNJ
