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Pharmacol Rep 72(3):692704 Elkamhawy A, Paik S, Park J-H, Kim HJ, Hassan AH, Lee K et al (2021) Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinsons disease (PD): design, synthesis, in vitro, in vivo and in silico biological studies

Using statistically sound techniques, such as random, stratified, composite, and target sampling, ensures legal and valid results (Enkerlin et al., 2019)

Exogenous transport mechanisms Focused ultrasound Focused ultrasound (FUS) is a non-invasive technique that temporarily disrupts the BBB

In parallel, adenosine-5-phosphosulfate can be further phosphorylated to 3-phosphoadenosine-5-phosphosulfate, which is used for sulfation reactions (Mugford et al., 2011

Nature 481 , 365370 (2011)
