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In their study, titled Depressive state and chronic fatigue in multiple sclerosis and neuromyelitis optica, published in the Journal of Neuroimmunology , researchers decided to study depression, fatigue and the use of l-carnitine in seventy-five patients with MS and 39 patients with NMO at Tohoku University Hospital in Japan

Glutamate is the most abundant excitatory neurotransmitter in the central nervous system of adult mammals and has a major role in neuroplasticity (Henter et al., 2017

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This step is the primary rate-limiting bottleneck of fatty acid oxidation

doi: 10.1159/000073347