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People who feel run down often, recover slowly, or carry lingering inflammation, and anyone who wants to feel more resilient through seasonal changes or travel
"Hundreds of thousands of kids, in my opinion, will benefit." The FDA still hasn't made that label change

BMC Immunol
That is not inherently a problem for maintenance, but for patients dealing with active acne, resistant hyperpigmentation, or post-inflammatory scarring, those concentrations often fall short of what the skin needs

Neurosci Lett 400(12):158162 Notarianni LJ (1990) Plasma protein binding of drugs in pregnancy and in neonates