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In a pioneering study, Luo et al

McGehee and Mori, 2024)

If you experience any suspected side effects from B12 supplementation (such as injection site reactions, allergic responses, or other unexpected symptoms), report these through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

Groups were assigned as MTX-vehicle, NTZ-100, and NTZ-200 groups (at 100 and 200 mg/kg/day, gavage, respectively), N-acetyl cysteine (NAC) group (500 mg/kg), and 4-phenyl butyric acid (4-PBA) group (150 mg/kg, i.p)

After 30 min the cells were washed with buffer and stained with DCFDA according to manufacturers instruction
