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Despite the growing interest in the spices-derived phytocompounds (e.g., alkaloids, terpenoids, polyphenols, fatty acids), there is still a paucity of research exploring their mechanism and efficiency as antifungal and antibiofilm agents against candidiasis

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The removal of superoxide radicals by SOD prevents the formation of the much more damaging peroxynitrite ONOO (O2 +NOONOO) and maintains the physiologically relevant level of nitric oxide (NO), an important molecule in neurotransmission, inflammation, and vasodilation

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When comparing with some well-known inhibitors of system xc, erastin was the most efficient inhibitor acting at low micromolar concentrations

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