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The increasing human population and rising demand for animal-based products are driving up maize consumption

The antioxidant enzyme activity of nanomaterials is influenced by factors including size, morphology, surface modification, and composition (185)

PI3K/Akt is a pathway that modulates pro- and anti-inflammatory processes, with the capacity to promote the production of pro-inflammatory cytokines (IL-6, IL-1) (164169) while concomitantly reducing excessive inflammation by inducing anti-inflammatory cytokines such as IL-10 (170172) Inhibition of FOXO by Akt leads to the inhibition of autophagy, production of antioxidant enzyme and apoptosis, thereby promoting a state of chronic inflammation (173, 174)

However, most short synthetic oligonucleotides (ASO or siRNA), aside the ones delivered by LNPs, do not contain natural RNA in view of its nuclease lability
