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TMQ0153-induced oxidative stress triggers DNA damage and intrinsic apoptosis Considering the effect of TMQ0153 on mitochondrial dynamics, integrity, and metabolism, we investigated the involvement of ROS generation in TMQ0153-induced cell death

Indeed, knockdown of RelA not only decreases p65 phosphorylation but also HIF-1 protein level in B cells stimulated by LPS for 4 h (Supplementary Fig

For these reasons nicotinic acid therapy is not recommended for diabetics or persons who suffer from gout

10.1016/j.jad.2011.12.041 J

Leukocytes were enriched by Percoll gradient centrifugation from enzymatically digested kidneys, and the numbers of neutrophils, macrophages, and monocytes were determined by flow cytometry