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For example, osteoblasts express receptor activator of NF-kB (RANK) ligand (RANKL) to activate the RANK on the surface of osteoclast precursors, and induce the differentiation of the latter cells (66)

Toxicology in vitro 2008, 22 (4), 927934

Therefore, the combination of both approaches (Figure 1) not only optimizes therapeutic effects but also promotes a shift in nursing models from experience-driven to data-driven, making nursing more scientific and precise, while significantly enhancing patient satisfaction and treatment adherence (201)

The imidazole ring on carnosine has a pKa of 6.83, allowing it to accept protons and reduce muscle acidity [28,29]

Nat Cell Biol 2008;10:676687
