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As shown in Figure 9B, the common targets of main ingredients and AD in FRP are mainly enriched in signal transduction, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, negative regulation of the apoptotic process, response to the drug, positive regulation of gene expression, positive regulation of cell proliferation, response to xenobiotic stimulus, positive regulation of transcription, DNA-templated, positive regulation of MAPK cascade
Additionally, higher mRNA expression of GLS has been detected in KRAS-mutated non-small cell lung cancer (NSCLC) [93]
We recently reviewed the objective methods of measuring sleep and circadian rhythms [90]
Nasal administration Some research and commercial products explore nasal DSIP delivery
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