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Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

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Tomiyasu H, Goto-Koshino Y, Takahashi M, Fujino Y, Ohno K, Tsujimoto H

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These findings provide a novel insight into the targets of GSH in ferroptosis as well as possible molecular mechanisms involved, suggesting the possible use of GSH as a combined therapy for treating OC

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In one study using the EAE model, invesigators demonstrated that SF (282 mol/kg/day for 14 days before EAE induction and 28 days after EAE induction) had anti-inflammatory effects, improved clinical scores in behavioral study, and inhibited demyelination in the spinal cords (92)

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25 (1), 156183 (2022) M

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