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D.LaButtiK.LipzenA.et al (2015)

Collectively, the data indicate that compound R3 is particularly effective in inhibiting inflammation mediated by prostaglandins and leukotrienes, while showing limited activity against histamine- and bradykinin-induced responses

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Eventually, the suppressed production of pro-inflammatory cytokines reduces hepatic and adipocyte pro-inflammatory cytokine gene expression, and enhanced anti-inflammatory cytokine gene expression is evident (99)

These findings highlight their excellent protection against UV-induced degradation