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Mitochondrial complex I is considered one of the primary sources of ROS and increased oxidative stress resulting from ROS production is one of the proposed mechanisms for the death of dopaminergic neurons in PD 23

[DOI] [PMC free article] [PubMed] [Google Scholar] Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, Pallanck LJ

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[DOI] [PMC free article] [PubMed] [Google Scholar] 485.Dong F, et al