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Multiple cytokines and inflammatory factors participate in keloid formation, such as transforming growth factor 1(TGF-1), vascular endothelial growth factor (VEGF), interleukin (IL)-1, IL-6, and IL-8, as well as increased matrix metalloproteinases (MMP S ), which may promote fibroblast proliferation and migration, the inflammatory response, and collagen production 2,3,4

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The first line of defense against sulfide toxicity is often sulfide:quinone oxidoreductase (SQR), an enzyme that catalyzes the oxidation of H 2 S to sulfane sulfur (S 0 ), bound to a low-molecular-weight (LMW) thiol such as glutathione (GSH) to form a LMW thiol persulfide, e.g

Research has even shown that glutathione can help prevent the hardening of the arteries (atherosclerosis) by keeping cell walls strong and elastic

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