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Watanabe M, Hida A, Kitamura S, Enomoto M, Ohsawa Y, Katayose Y, et al
INR/PT Elevated PT has a strong predictive value for the development of hepatotoxicity
Internal changes during this phase include upregulation of collagen genes, increased growth factor production, and early accumulation of new extracellular matrix components
Imatinib and vemurafenib block platelet-derived growth factor receptor (PDGFR) and BRAF respectively, and drug combination has a positive impact on TC elimination through inactivating HK2 [270]
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