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Class II consists primarily of Sigma class GSTs as identified in , DmGSTS1 [66] and , AgGSTS1 [67]

According to the Global Burden of Disease Study 2023 [consistent with (2) but more precise], MDD affects approximately 280 million people globally, accounting for 3.6% of the total population

Pharmaceutical Biology, 42(3), 240245

At the same time, the complex regulation of skin pigmentation is much better understood with increased knowledge on the physiopathology of pigmentary disorders, beyond the sole melanogenesis, including the whole tissue environment of melanocytes

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