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doi: 10.1016/j.biopsych.2004.02.009

This is when wrinkles start to reappear and a touch up may be required

VenierNAYamamotoTSugarLMAdomatHFleshnerNEKlotzLHet al
The maximum C1-27 treatment-related weight loss during the course of the study did not exceed 12% (Supplementary Fig

10.1002/ddr.21981 Drug Dev