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Some classes conjugate GSH with epoxides and catalyze isomerization or reduction of harmful peroxides [52]

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These factors substantially increase the risk of cardiovascular illnesses and lead to systemic metabolic disturbances [92]

Future research needs to pay attention to this point, and whether calmangafodipir can also protect neuropathy from other chemotherapy drugs remains to be further explored

Injectable administration is generally preferred when maximizing potency, dosing precision, and consistent therapeutic response is the primary goal