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In contrast, DHODH is anchored within the inner mitochondrial membrane and couples the oxidation of dihydroorotate to orotate with CoQ reduction, producing a localized reservoir of CoQH that specifically protects mitochondrial membranes from ferroptotic damage

[DOI] [PMC free article] [PubMed] [Google Scholar] 401.Liang, K

J Affect Disord 111(23):135144

Coles LD, Tuite PJ, z G, Mishra UR, Kartha RV, Sullivan KM, Cloyd JC, Terpstra M (2018) Repeated-dose oral N-acetylcysteine in Parkinsons disease: pharmacokinetics and effect on brain glutathione and oxidative stress

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