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The most commonly reported b12 injection side effects include localised pain or redness at the injection site, mild nausea, headache, or a brief sensation of warmth or flushing shortly after administration

A causal role for portal hypertension in the pathogenesis or further progression of the barrier defect in chronic liver disease is suggested by an improvement of intestinal permeability and LBP levels with non-selective beta-blockers and transjugular intrahepatic portosystemic shunting (TIPS) (156, 157)

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However, as autoantibodies to AChR are found in the majority of individuals with myasthenia gravis [187, 188], the specificity of this as a diagnostic biomarker needs to be investigated further