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(2020) identified artesunate, an artemisinin derivative, that interacts with PDXK in a specific manner by competitively inhibiting the PL binding region, effectively inhibiting PLP biosynthesis
mTOR: Mammalian target of rapamycin
Research suggests it may regulate thousands of genes associated with tissue regeneration, DNA repair, inflammation control, and healthy cellular aging
Heterozygous parents and siblings of these patients are healthy with no symptoms, which clearly indicates an autosomal recessive disorder
J Hazard Mater 430:128459
