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SOD and GPx further neutralize superoxide radicals and hydrogen peroxide

10.1111/j.0953-816X.2004.03397.x 116 KellyJ.MoyeedR.CarrollC.LuoS.LiX

Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults

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Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart