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Effects of resveratrol on HepG2 cells as revealed by (1)H-NMR based metabolic profiling

CENPT is found to be critical for regulating the glutathione (GSH) metabolism pathway because it interacts with -glutamyl-cysteine ligase catalytic subunit (GCLC), consequently reducing reactive oxygen species levels and inhibiting ferroptosis

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In a typical test, certain amounts of TMB (final concentration 500 M) and PtCo@G were added into buffer solution (25 mM PBS, pH 4.0), and then UV-Vis absorption spectra were recorded at different times using a UV-2450 UV-vis spectrophotometer (Shimadzu, Japan)

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