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Fortunately, B12 supplementation can help to improve these symptoms, with improvement typically seen within days to weeks

Pre-clinical studies suggest that low B12 may contribute to fat accumulation and disrupt lipid metabolism (how the body processes and uses fats for energy and storage)[1]

Another rat study over 19 days showed reduced body weight gain compared to a control group, and increased lipolytic activity in the treatment group

It is important to continue with the prescribed course of injections even if you do not feel immediate improvement

[1] [4] Mood changes including low mood, irritability, or anxiety can be associated with declining B12 levels, though these symptoms are non-specific and can have many causes