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The convergence of these influences suggests that disruptions in microbial homeostasis could contribute significantly to the development and perpetuation of ME/CFS [10, 33]

Accordingly, similar to the heme system of hemoglobin where the upper axial ligand O 2 can be easily exchanged, the upper axial ligand of B 12 is also exchangeable

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Iron (III) induces aggregation of hyperphosphorylated and its reduction to iron (II) reverses the aggregation: Implications in the formation of neurofibrillary tangles of Alzheimers disease

Environ Mol Mutagen 40:292299 Moore MM et al (2003) Mouse lymphoma thymidine kinase gene mutation assay: international workshop on genotoxicity tests (IWGT) workgroup report-Plymouth, UK 2002