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Endothelial dysfunction is characterized by the reduction of bioavailability of NO, resulting in impaired endothelium-dependent vasodilation (69) and increased oxidative stress (70)
However, ILD can be the primary manifestation of systemic autoimmune disease in a small percentage of patients
7, July 2011, p
doi: 10.1016/j.eururo.2015.09.026
The patient cohorts often widely differed in number of subjects, age, disease severity, and many other factors
