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Additionally, a combination of CCNA1 (cyclin A1) and VIM biomarkers has demonstrated a sensitivity of 90.3% and a specificity of 91.7% in detecting BE metaplasia following DNA methylation (Moinova et al., 2018)

A growing body of evidence indicates that MYPT1 is also significant in various non-contractile functions, such as cell adhesion and migration, cell division, cell proliferation, neurotransmitter release, embryonic development, and the regulation of both endothelial and epithelial barrier functions [76, 77]