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The role of serum albumin in the prediction of malnutrition in patients at least five Yr after heart transplantation

It inhibits the thioredoxin-interacting protein (TXNIP), a key regulator of ROS production, which in turn downregulates the NLRP3 inflammasome, reducing inflammation and oxidative stress-induced tissue damage

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The role of iron Lipid peroxidation is facilitated by the labile iron pool, which enhances the Fenton reaction to propagate lipid peroxidation, and by iron-dependent enzymes that initiate lipid hydroperoxide formation [22]