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Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacterial overgrowth, total or partial gastrectomy

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Other candidates include people who've experienced nerve damage from nitrous oxide exposure (sometimes called "laughing gas neuropathy") and those battling unexplained fatigue or neurological symptoms that haven't responded to other treatments

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Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in rats