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How L-Carnitine Works in Fat Metabolism L-carnitine functions as a shuttle molecule that transports long-chain fatty acids into mitochondria, the cellular powerhouses where fat oxidation occurs
This result solidified the notion that the Met35 residue of A42 is critical to the oxidative damage and neuronal death associated with this neurotoxic peptide
In particular, short-chain acylcarnitines, such as acetylcarnitine, which are thought to rather support neuronal function [29], were decreased in the plasma of MDD patients, and more harmful medium- and long-chain acylcarnitines were increased in several studies [73]
