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Finally, we performed a comparative transcriptome analysis from livers of 5 and 20 months old wt and C/EBP uORF female mice (Mller, 2018)

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3.1.3 Chemotherapy induces long-term (LT)-BM injury by reducing the self-renewal and proliferation ability of HSCs But in certain cases, thrombocytopenia persists and does not recover even in the subsequent chemotherapy cycle, and these patients experience LT-BM injury after chemotherapy due to HSC damage [66]