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Honeys antioxidant activity is largely owed to its abundant polyphenol and flavonoid content through three synergistic mechanisms: (i) neutralization of reactive oxygen species (ROS), (ii) upregulation of several antioxidant enzymesincluding SOD, GR, GPx, and CAT, and (iii) transcriptional regulation of genes involved in redox balance (114, 115)

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Neurobiol Dis 2024:106520 Bedini A et al (2024) Industrial and academic approaches to the search for alternative melatonin receptor ligands: an historical survey

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