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22 Reverse Mendelian randomization evidence suggests that genetic susceptibility to Graves disease is associated with low circulating vitamin A, meaning that vitamin A deficiency promotes the development of autoimmunity in the genetically predisposed

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Also, in the presynaptic neuron, palmitoylation of SNAP-25 directs it to partition in the cell membrane [17] and allows the SNARE complex to dissociate during vesicle fusion

Furthermore, diabetes upregulates lysophosphatidylcholine acyltransferase-3 (LPCAT3), facilitating the integration of polyunsaturated fatty acids (PUFA) into phospholipid membranes, and downregulates acyl-CoA thioesterase-1 (ACOT1), which further promotes ferroptosis

demonstrated long-term DMF treatment significantly resulted in improvement in beta-cell function in rats with CP [83]