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Supplementation with probiotics, particularly Lactobacillus and Bifidobacterium strains, has shown immunomodulatory effects and enhanced epithelial barrier integrity [140,141,142]
NLRP3 inflammasome activation requires two signals: the initiation of NLRP3 gene transcription through the NF-B pathway and the activation of NLRP3 inflammasome sensors [67]

Do not use direct heat (such as hot water, a heating pad, or a heat lamp) to warm the person
Pagliaro L, et al

doi:10.1079/BJN19980055 86
