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Zwitterionic small molecules, including SNAC (sodium N-[8-(2-hydroxybenzoyl) amino] caprylate), improve peptide solubility and permeability, and are key components of marketed oral peptide drugs like Rybelsus , demonstrating their translational potential [98]

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, Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials, Lancet , vol

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