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Description
The activation of the Nrf2 pathway triggers a massive endogenous production of Phase II detoxification enzymes, including Heme Oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase 1 (NQO1)

F.YantiriF.et al (2001)

As a result, controlling oxidative stress has become a key neuroprotective strategy

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Grka P., Kowalski Z.M., Zabielski R., Guilloteau P

Most people who carry one normal and one defective copy of the HFE gene do not develop hemochromatosis symptoms
