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10.1002/ajh.27102 163

Neuroprotective effects of a novel poly(ADP-ribose) polymerase-1 inhibitor, 2-[3-[4-(4-chlorophenyl)-1-piperazinyl] propyl]-4(3H)-quinazolinone (FR255595), in an in vitro model of cell death and in mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinsons disease

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They discovered that although this treatment reduced cramp frequency, it failed to alleviate its severity in their studied population [27]

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