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Clinical studies confirm that chronic treatment with AOD9604 showed no adverse effect on insulin sensitivity, making it a metabolically selective approach to body composition optimization under medical supervision

doi: 10.1159/000437098

[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Longstreth WT, Manolio TA, Arnold A, Burke GL, Bryan N, Jungreis CA, Enright PL, OLeary D, Fried L

This finding suggests that, in certain contexts, the activation of the ERK/MAPK pathway may act as an upstream mediator of copper-induced cell death

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