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The pathological shift toward M1 polarization results in heightened secretion of pro-inflammatory cytokines and enzymesincluding TNF-, IL-1, IL-6, IL-23, IFN-, inducible nitric oxide synthase and cyclooxygenase-2thereby driving neuroinflammatory processes and contributing to neuronal degeneration 58

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1991;13((Suppl

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Detoxifying harmful substances in the liver for safer elimination

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