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Then, the DNA and PEI in Opti-MEM were mixed and further incubated for 30 min at room temperature, and the mixture was added to the 28 ml culture of HEK293 cells at 1 10 6 cells/ml

Acknowledgements The work was partially supported by the Research Council of Norway through its Centres of Excellence scheme, project number 332727, and grant 274993 (J.T.A., J.N., and S.B.), grant 287927 (J.T.A., K.H.A., and F.R.J.), and grant 285136 (J.T.A.)

Technical Information INCI Name: Copper Tripeptide-1 Common Name: GHK-Cu (Copper Peptide) Appearance: Bright blue to deep-blue fine powder Chemical Composition GHK-Cu is a copper-binding tripeptide complex composed of: Glycine L-Histidine L-Lysine Copper ions (Cu) Molecular Formula: CHNOCu Solubility: Water soluble Recommended Cosmetic Applications Suitable for cosmetic formulations including: Serums Creams Gel formulations Scalp formulations Cosmetic skincare applications Grade: Cosmetic-Grade Raw Powder Storage Guidelines Store in a cool, dry environment Protect from direct sunlight and excessive heat Keep container tightly sealed between uses Avoid moisture exposure during handling For Cosmetic Formulation and Research Use Only Not for injection or human consumption

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