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The sirtuins are NAD + -dependent deacetylases that are distributed in the nucleus (e.g., SIRT1, SIRT6, and SIRT7), the cytoplasm (e.g., SIRT2) and mitochondria (e.g., SIRT3-5), respectively
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Population estimate of people with clinical AD and mild cognitive impairment in the United States (20202060)
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