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TABLE 2 Alternative approaches to targeted inhibition of ferroptosis

Animals were housed in ventilated microisolator cages (46 mice/cage) under specific pathogen-free conditions with 12:12 light-dark cycles, ad libitum access to autoclaved food and water

Binding analysis of methyl-cpG binding domain of meCP2 and rett syndrome mutations

[Google Scholar] [206].Zhang Y, Leonessa F, Clarke R, Wainer IW, Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities, J

For example, NMR-titration experiments of non-glutathionylated poplar GrxC4 or ScGrx8 with GSH required high glutathione concentrations to detect chemical shifts 47,48 (and titrations of active site serine mutants with GSSG cannot discriminate between both glutathionyl moieties)