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Neurons and astrocytes both preferentially express the mitochondrially-located, kidney-type glutaminase (GLS) isoenzyme type 1 (GLS1), although there is also the liver-type GLS2 that localizes to the mitochondrion and nucleus (Cardona et al., 2001

4 Department of Anatomy & Cell Biology, University of Florida, Gainesville, Florida, USA

Similarly, 2,2-Bipyridyl (2,2-BP) and 1,10-Phenanthroline (1,10-PT) chelate mitochondrial iron, reducing ferroptosis and mitochondrial ROS accumulation in vitro , particularly in models involving zero-valent iron nanoparticles (Huang et al., 2019

Appears to be able to recycle antioxidants such as vitamin C and glutathione after they have been used up

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